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Symbol Name ID |
Rbfox3
RNA binding protein, fox-1 homolog (C. elegans) 3 MGI:106368 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | nervous system phenotype |
increased susceptibility to pharmacologically induced seizures |
abnormal neuron differentiation |
decreased neuronal precursor proliferation |
decreased brain weight |
abnormal brain white matter morphology |
abnormal hippocampus granule cell morphology |
abnormal hippocampus neuron morphology |
increased dendritic spine density |
abnormal dentate gyrus neuron dendrite morphology |
decreased neuronal precursor cell number |
abnormal excitatory synapse morphology |
abnormal hippocampus physiology |
impaired synaptic plasticity |
abnormal CNS synaptic transmission |
abnormal excitatory postsynaptic potential |
abnormal miniature inhibitory postsynaptic currents |
increased miniature inhibitory postsynaptic current frequency |
reduced long-term depression |
increased neurotransmitter release |
decreased paired-pulse facilitation |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Rbfox3tm1a(EUCOMM)Hmgu/Rbfox3tm1a(EUCOMM)Hmgu | * | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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